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The situation for 1,25(OH) 2 D is more complex. Addition of serum proteins or pure DBP to cell cultures clearly decreases the biological activity of 1,25(OH) 2 D as studied by gene transcription or cellular functions, again demonstrating the sequestering characteristics of DBP, bulking prohormones 2022. However, the affinity of intracellular VDR for 1,25(OH) 2 D by far exceeds its affinity for DBP so that over time a favorable transport from extracellular to intracellular compartment is likely. This could then explain why the distribution volume of 1,25(OH) 2 D corresponds to the intracellular fluid volume (and thus much higher than the 25OHD distribution volume). Characteristics of Human Vitamin D-Binding Protein.
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Bulking prohormones 2022, steroids tattoo
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